Robin Holliday's Aging: The Paradox of Life PDF

By Robin Holliday

ISBN-10: 1402056400

ISBN-13: 9781402056406

ISBN-10: 1402056419

ISBN-13: 9781402056413

For hundreds of years humans were wondered through the inevitability of human getting older. for many of the second one 1/2 the 20 th century getting older remained a secret, or an unsolved organic challenge. on the finish of the twentieth century a outstanding medical discovery emerged. It used to be now not a unmarried discovery within the ordinary experience, since it used to be in line with a chain of significant interconnected insights over rather an extended time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it might probably already be acknowledged, besides the fact that, that the various observations and insights that specify getting older usually are not accredited as proven wisdom for a very long time. the sector continues to be filled with scientists, and non-scientists, who're simply chuffed to move on speculating in regards to the 'mystery' of getting older. the purpose of this publication is to dispel lack of awareness by way of explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of existence.

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Such enzymes are an essential part of our digestive system, but within cells their role is much more subtle and discerning. They have to recognise abnormal molecules, and leave normal ones intact. This ability to discern abnormal and normal is only partly understood, but there is no doubt that it is an efficient process in all cells. The turnover of proteins occurs continuously during normal metabolism; many amino acids are re-utilised in the synthesis of new protein molecules, but some are degraded and end up as urea.

One of the characteristics of the overall ageing process, or set of processes, is that a partial failure of one organ system can impinge on another. A good example of this is the increase in blood pressure that occurs during ageing. This may be largely due to the loss of elasticity of the walls of major arteries (hardening of the arteries). High blood pressure has deleterious effects, and may in the end lead to kidney failure, and the requirement of a dialysis machine, or a kidney transplant. High blood pressure can also result in the rupture of a brain artery, and a slight or a severe stroke may result.

This becomes a semantic issue, because ageing is itself a time-dependent process, or more accurately, a set of processes In cancer, it is thought that the events must occur successively in a given cell lineage, because it is well known that tumours originate for a single precursor cell. The events could be mutations, and the chance of any individual cell acquiring all these genetic changes will be very small. Unfortunately, because there are so many cells in the body, the probability that at least one of them will eventually become cancerous becomes quite high.

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Aging: The Paradox of Life by Robin Holliday

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