Robin Holliday's Ageing : the paradox of life PDF

By Robin Holliday

ISBN-10: 1402056400

ISBN-13: 9781402056406

For hundreds of years humans were wondered by means of the inevitability of human getting older. for many of the second one half the 20th century getting older remained a secret, or an unsolved organic challenge. on the finish of the twentieth century a impressive medical discovery emerged. It was once no longer a unmarried discovery within the traditional feel, since it used to be in response to a sequence of significant interconnected insights over rather an extended time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it might already be acknowledged, even if, that the various observations and insights that designate getting older aren't permitted as tested wisdom for a very long time. the sphere remains to be packed with scientists, and non-scientists, who're simply chuffed to move on speculating in regards to the 'mystery' of getting older. the purpose of this booklet is to dispel lack of awareness via explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of existence.

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Extra resources for Ageing : the paradox of life

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One example of this is the greying and whitening of hair, or the loss of hair. This in no way can be regarded as a pathological change. Similarly, the wrinkling of skin is a major characteristics of ageing, yet by itself it does not cause much harm. It is due to progressive changes in the dermis and epidermis, and particularly the loss of elasticity. It is a symptom or manifestation of ageing, but not a cause. Muscle strength declines with age, which due to a loss of weight and volume of muscle tissue.

This balance is lost in the late decades and bone strength declines, leading to osteoporosis and the increased likelihood of fractures. The immune system consists of many different components, which must operate as an integrated unit. It is well known that the efficiency of immunity declines with age, probably because individual components are not making their normal contribution to the whole. Old people become more susceptible to infections such as influenza or pneumonia. Multiple Causes 29 The immune system is capable of distinguishing self from non-self, and that is why grafts of tissue from other individuals are destroyed.

It is likely that cells with two sets of chromosomes, and therefore with two copies of each gene, allowed organisms to store much more genetic variability, since the two genes of each type could have slight, but significant, differences in their DNA. The cell division which produces nuclei with only one copy of each gene, also re-assorts different genes into a multitude of different combinations. Thus, all the progeny in sexual reproduction are genetically different from each other, whereas in asexual reproduction they are all the same, forming a clone.

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Ageing : the paradox of life by Robin Holliday

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